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Quattroflow Pumps

How does a pump have to be designed to convey extremely delicate biologically active molecules? A couple of million years of evolution selected the perfect device to pump albumin, gamma globulins, clotting factors and cells: it is the heart.

Quattroflow are 4-piston-diaphragm pumps. The stroke of each of the 4 pistons is created by an eccentric shaft, which is connected to an electric drive. They are specifically designed for the critical applications in the pharmaceutical and biotech industry. Whether in cross-flow systems, chromatography devices or centrifuges, the Quattroflow pumps gently convey aqueous solutions and biological products sensitive to shear force ranging from blood to vaccines without denaturing them.

Quattroflow pumps are sold worldwide and used at numerous biotech and pharmaceutical companies, including such industry leaders as Aventis, Baxter, Chiron, Roche, Sandoz, Boehringer Ingelheim.


• Nearly no pulsation, exact dosing achievable.
• Quiet operation.
• Pump body made of stainless steel 316L (1.4435), 904L (1.4539), or others, and electopolished as an option. This means low ferrite content and no problems with high-salt buffers. If stainless steel does not fit, pump body is made of peek.
• Few parts and long lifetime diaphragm make the pumps easy to maintain and service.
• No mechanical shaft seal, no rotating parts in the fluid mean no leakage, no particle shedding, nearly no heating a product.
• Aseptic clamps.
• Self-priming, the pumps can be mounted above a vessel.
• Can run dry.
• 4 directions of flow enable flexible location.

Typical Applications

• Feed and recirculation pump in all kinds of cross-flow systems with cassettes, spiralwound, hollow fibre or ceramic modules.
• Feed and/or dosing pump in chromatography systems (product and buffer).
• Feed pump for centrifuges, separators and homogenisators.
• To pump product solutions through cartridge filter systems (e.g.: fine, sterile filtration, and virus removal).

Examples of media pumped with Quattroflow:

• Blood derived plasma protein solutions, such as: Human Serum Albumin, IgG, Clotting factors, etc.
• Cell culture supernatants: monoclonal antibodies, etc.
• Cell broths: bacteria, yeast, mammalian cells, etc.
• Virus containing broths.
• Bacterial and viral vaccines.
• Enzyme solutions.


Parameter Quattroflow 1000 S Quattroflow 4000 S
Flow rate approx. 1000 L/hr at 0 bar,
approx. 750 L/hr at 6 bars
approx. 5000 L/hr at 0 bar,
approx. 3200 L/hr at 6 bars
Max. pressure 6 barsΉ 6 bars
Temperaure of fluid max. 60°C²
CIP 90°C
max. 60°C
CIP 90°C
Speed 0...1800 rpm 0...1200 rpm
Material of pump body Stainless steel 316L  (1.4435) or 904L (1.4539)³ Stainless steel 316L  (1.4435) or 904L (1.4539)³
Diaphragm Santoprene, EPDM, Silicon Santoprene
Inlet/Outlet 3/4" TC (ISO 2852)
acc. to customer request
1.5" TC (ISO 2852)
acc. to customer request
Electric Drive AC motor, 370W forced cooling fan (IP55) AC motor, 2.2 KW forced cooling fan (IP55)
Controlbox frequency inverter,
230 V~/50Hz (IP53)
frequency inverter,
400 V~/50Hz (IP53)
Weight without control box 23 kg 80 kg
Weight of control box 6 kg 12 kg
Dimensions (LxWxH) without control box 523 x 155 x 212 mm 770 x 250 x 357 mm
Dimensions (LxWxH) of control box 350 x 155 x 212 mm 530 x 250 x 330 mm

¹ Higher pressure versions are available upon request.
² Inline steam sterilisation is possible.
³ Material certificate acc. DIN EN 10204, 3.1 B is available.


Please contact us for more information or click links below to send us a quotation request.

Model Catalogue No. Price, CA$
Quattroflow 1000 S - Request
Quattroflow 4000 S - Request
Spare parts for Quattroflow 1000 S - Spare parts brochure
Spare parts for Quattroflow 4000 S - Spare parts brochure

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