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Hollow Fibre Modules:

• MicroKros

• MidiKros

• MiniKros Sampler

• MiniKros Sampler Plus

• MiniKros

• MiniKros Plus

• KrosFlo

• KrosFlo Plus

• KrosFlo Max

• CellFlo

ŧ CellFlo Plus

• CellFlo Max

• KrosFlo SIP

 

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CellFlo Plus Modules

Hollow Fibre Modules with Advanced Connection Design for Cell Separations, 0.5 to 1000 L



Overview

CellFlo Plus modules are hollow fibre TFF for gentle and efficient cell separations with a variety of convenient connection options. Plus connections provide a multitude of system connection combinations that simplify both the initial system set up as well as the replacement of disposable membranes, saving valuable time and reducing the risk of contamination.

CellFlo Plus modules are available in the same sizes and surface areas as popular CellFlo pilot scale and lab scale modules with the same high quality and disposable pricing. All CellFlo Plus membrane use 1 mm ID hollow fibre membrane to reduce shear stress with a pore rating of 20 nm, 0.2 ĩm or 0.5 ĩm. CellFlo Plus can either be autoclaved or purchased irradiated (irr).

CellFlo Plus Modules

Applications

• Continuous cell perfusion
• Cell washing and/or harvesting
• Clarification of cellular debris for protein

• Bacterial fermentation harvesting
• Monoclonal antibody production
• Processing diagnostic micro-particles

Lab Scale CellFlo Plus Modules

Cell perfusion for labs

Ideal for cell perfusion of 0.5 to 100 litres, the narrower lab scale CellFlo Plus modules are available in the three inlet/outlet port options: 1.5" TC sanitary, 3/4" TC sanitary or 1/2" hose barb. All three types have 1/2" hose barb filtrate ports.

Parameter Description
Housing Clear and pigmented polysulfone
Inlet/Outlet Ports 1.5" sanitary, 3/4" sanitary or 1/2" hose barb
Filtrate Ports 3/8" hose barb
Potting Polyurethane
Process Volume 0.5 - 100 L
Surface Area 500 - 6200 cmē

Membranes Fibre ID MWCO
Mixed Cellulose Ester (ME) 1.0 mm 0.2 µm
Polyethersulfone (PES) 1.0 mm 0.2 µm, 0.5 µm
Polysulfone (PS) 1.0 mm 20 nm, 100 kD

Surface Area (cm²) ID (mm) TL (cm) L (cm) EL (cm) Dimensions
500-620 18.8 8.6 23.5 20.6
1500-2000 31.2 28.6 23.5 20.6
3200-4200 31.2 48.1 47.2 44.0
4800-6200 31.2 73.8 69.0 65.8

Pilot Scale CellFlo Plus Modules

Cell perfusion for production

Ideal for volumes from 3 to 1000 litres, the larger pilot scale CellFlo Plus modules are available with the option of 1.5" TC sanitary, 1/2" hose barb or 3/4" hose barb inlet/outlet ports and 1.5" TC sanitary, 1/2" straight or 3/8" hose barb filtrate ports. A threaded nut and gasket is used to secure the inlet/outlet end-cap in place.

Parameter Description
Housing Clear and pigmented polysulfone
End Cap and Nut Pigmented polysulfone with female thread
Gasket Silicone
Inlet/Outlet Ports 1.5" sanitary, 1/2" hose barb or 1/4" hose barb
Filtrate Ports 1.5" sanitary, 1/2" straight or 3/8" hose barb
Potting Polyurethane
Process Volume 3 - 1000 L
Surface Area 0.31 - 4.1 mē

Membranes Fibre ID MWCO
Mixed Cellulose Ester (ME) 1.0 mm 0.2 µm
Polyethersulfone (PES) 1.0 mm 0.2 µm, 0.5 µm
Polysulfone (PS) 1.0 mm 20 nm

Surface Area (m²) ID (mm) TL (cm) L (cm) EL (cm) Dimensions
0.31 - 1.3 70.0 28.1 22.9 20.0
1.8 - 2.6 70.0 51.3 46.0 41.5
2.8 - 4.1 70.0 74.4 69.1 65.0

Please contact us for current prices, more technical details or assistance.

Phone (403) 287-2345 • Toll-free 1-(800)-565-2345 • Fax (403) 287-1355 • E-mail: sincaninc@telus.net

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