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Hollow Fibre Modules:

• MicroKros

• MidiKros

• MiniKros Sampler

• MiniKros Sampler Plus

• MiniKros

• MiniKros Plus

ŧ KrosFlo

• KrosFlo Plus

• KrosFlo Max

• CellFlo

• CellFlo Plus

• CellFlo Max

• KrosFlo SIP


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KrosFlo Modules

Disposable Hollow Fibre Tangential Flow Modules for Pilot Production,  3 to 1000 L


The disposable KrosFlo hollow fibre filter is the ideal device for the quick filtration of production scale volumes resulting in high product yields. Hollow Fibre Tangential Flow is the most efficient filtration alternative for the gentle processing of delicate applications like cellular harvesting and antibody production. It has become the industry standard for processing latex microparticles.

The KrosFlo module consists of high quality hollow fibre membranes potted in a chemically resistant polysulfone housing for product recirculation through 3-inch sanitary inlet/outlet connections and filtrate collection via 1 1/2 inch sanitary side connections. The hollow fibre membrane geometry and capillary flow dynamics provide consistent filtration performance and direct scalability from process development to production scales. Since the KrosFlo filters are disposable, FDA validation has never been easier. All modules are autoclavable or are available irradiated (irr).

KrosFlo Modules
KrosFlo Pharma System


• Diafiltration of diagnostic particles
• Cell washing and/or harvesting
• Clarification of cellular debris for
protein or virus

• Protein purification and concentration
• Monoclonal antibody production
• Purification and concentration of virus
• Nanoparticle diafiltration


Parameter Description
Housing Clear and pigmented polysulfone
Connections 3" sanitary tri-clover (TC) inlet/outlet ports;
1.5" sanitary tri-clover (TC) inlet/outlet ports
Potting Polyurethane
Process Volume 3 - 1000 L
Surface Area 0.3 - 5.1 mē

Membranes Fibre ID MWCO
Mixed Cellulose Ester (ME) 0.6 mm 0.1 µm, 0.2 µm
Polyethersulfone (PES) 0.5 mm 0.2 µm, 0.5 µm
Polysulfone (PS) 0.5 mm 0.05µm, 20 nm, 400 kD, 100 kD, 50 kD, 10 kD

Surface Area (m²) ID (mm) TL (cm) L (cm) EL (cm) Dimensions
0.32-1.6 70 22.9 22.9 20.0
1.8-3.3 70 46.7 46.0 41.5
2.8-5.1 70 69.1 69.1 65.0

Please contact us for current prices, more technical details or assistance.

Phone (403) 287-2345 • Toll-free 1-(800)-565-2345 • Fax (403) 287-1355 • E-mail: sincaninc@telus.net

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